Author

Mehmet Hakan Guney

University of Massachusetts Chan Medical SchoolORCID 0000-0002-9080-7128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jeremy LubaniD· 3 shared Sean Matthew McCauleyiD· 2 shared Ann DauphiniD· 1 shared Carl D. NovinaiD· 1 shared Claudia CarboneiD· 1 shared David K. YangiD· 1 shared Dustin S. GriesemeriD· 1 shared Hilary K. FinucaneiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Jeremy LubanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedJul 10, 2024

IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus

Mehmet Hakan Guney, Karthika Nagalekshmi, Sean Matthew McCauley…·Jeremy Luban

This study identifies IFIH1 (MDA5) as essential for innate immune detection of intron-containing RNA from the HIV-1 provirus, linking it to chronic inflammation in HIV-1 patients.

29 citationstop 5%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsCellPeer-reviewedSep 1, 2021

Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution

Dustin S. Griesemer, James R. Xue, Steven K. Reilly…·Pardis Christine Sabeti

The paper identifies causal 3'UTR variants linked to human disease and evolution using a new high-throughput assay and functional analysis.

177 citationstop 1%

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyNature MicrobiologyPeer-reviewedSep 28, 2018

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

Leonid Yurkovetskiy, Mehmet Hakan Guney, Kyusik Kim…·Jeremy Luban

This study identifies Vpx and Vpr as viral proteins that counteract the HUSH complex to activate provirus transcription in primate immunodeficiency viruses.

143 citationstop 2%

humanexperimental assay

𝕏 PostBluesky