Author

Richard Barker Cook

University of SouthamptonORCID 0000-0002-2468-5820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aya A. Ben Issa· 1 shared Bram G. SengersiD· 1 shared David Annandale JohnstoniD· 1 shared Dichu XuiD· 1 shared Maria L. Hernandez-MirandaiD· 1 shared Martin BrowneiD· 1 shared Nicholas D. EvansiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Aya A. Ben Issa

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1 paper

Recent·Most cited

BiophysicsJournal of The Royal Society InterfacePeer-reviewedOct 1, 2024

Geometric constraint of mechanosensing in bone marrow stromal cell cultures prevents stiffness-induced differentiation

Maria L. Hernandez-Miranda, Dichu Xu, Aya A. Ben Issa…·Nicholas D. Evans

This study shows that in bone marrow stromal cells, matrix deformations and differentiation are influenced by ECM stiffness, geometry, and cell density, with high cell density reducing deformation differences between stiff and soft substrates.

6 citations

experimental assaycell type annotation

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