Danny Leung

The paper investigates how three-dimensional chromatin domain structures influence gene regulation and finds that domain surfaces are enriched for regulatory elements and disease variants.

This study identifies epigenetic changes in HCC that affect cis-regulatory elements and retrotransposons, linking them to gene dysregulation and poor prognosis.

The paper investigates how SARS-CoV-2 infection alters the transcriptome and epigenome at the maternal-fetal interface, linking these changes to adverse pregnancy outcomes.

This study shows that replication timing (RT) is essential for maintaining the global epigenetic state and genome compartmentalization in human cells, with RIF1 playing a central role in this process.