Molecular BiologybioRxivPreprint
Polypyrimidine Tract Binding Protein blocks microRNA-124 biogenesis to enforce its neuronal specific expression.
Kyu‐Hyeon Yeom, Simon A. Mitchell, Anthony J. Linares…·Douglas L. Black
The paper shows PTBP1 inhibits miR-124 biogenesis in mESCs, creating a regulatory loop that reinforces neuronal differentiation.
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