Detection of a sequence feature for recursive splicing
Bixuan Wang, Kevin Yang, Yoseph Barash…·Daniel R. Larson
The paper identifies sequence features associated with recursive splicing and develops a classifier to detect these features.
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National Cancer InstituteORCID 0000-0002-2489-944XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Bixuan Wang, Kevin Yang, Yoseph Barash…·Daniel R. Larson
The paper identifies sequence features associated with recursive splicing and develops a classifier to detect these features.
Gloria R. Garcia, Murali Palangat, Josquin Moraly…·Daniel R. Larson
This study identifies U2AF's role in regulating mitochondrial function by controlling translation and localization of nuclear-encoded mitochondrial mRNAs, with implications for disease.
Benjamin T. Donovan, Bixuan Wang, Gloria R. Garcia…·Daniel R. Larson
The paper applies a kinetic proofreading model to elucidate how transient U2AF binding leads to high fidelity splice site selection.
This paper applies Latent Dirichlet Allocation to nucleotide sequences to identify motifs and subtypes, showing its utility in characterizing heterogeneous signals and discovering regulatory factors.