Jun Liu

The paper uses SMART-epi to study how m6A modification affects RNP granule assembly and RNA interactions, revealing functional divergence among YTHDF proteins.

This study shows O-GlcNAc clusters modulate BRD4 phase separation, affecting transcription by altering condensate properties and gene expression programs.

This paper shows YTHDF2 upregulation and nuclear relocation enhance CD8 T cell polyfunctionality and tumor immunity by regulating gene transcription and mitochondrial fitness.

The paper develops a nanobody that specifically targets the NMN-activated state of SARM1, enabling structural analysis and functional studies of this conformation.

driverMAPS improves cancer driver gene detection by modeling positive selection and mutation patterns, identifying 159 new potential driver genes including RNA methyltransferases.