Author

Nathan J. Yu

Princeton UniversityORCID 0000-0002-2509-1725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ralph E. KleineriD· 3 shared Ang LiiD· 1 shared Isao MasudaiD· 1 shared Jingwei JiiD· 1 shared Muhan He· 1 shared Qais Z. JaberiD· 1 shared Wei Hao DaiiD· 1 shared Ya‐Ming HouiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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3 shared papersBiochemistry

Ralph E. KleinerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 24, 2026

Activity-based profiling of bacterial RNA-modifying enzymes reveals species-specific 5-methyluridine modification in Bacillus subtilis 23S rRNA

Qais Z. Jaber, Nathan J. Yu, Isao Masuda…·Ralph E. Kleiner

This study adapts RNABPP-PS to identify RNA-modifying enzymes in bacteria, revealing species-specific 5-methyluridine modification in B. subtilis 23S rRNA.

DOI 10.1073/pnas.2613881123

E. colihuman

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BiochemistryACS Central SciencePeer-reviewedMar 12, 2024

A minimal sequence motif drives selective tRNA dihydrouridylation by hDUS2

Jingwei Ji, Nathan J. Yu, Ralph E. Kleiner

This study identifies a minimal GU motif that directs hDUS2 to modify U20 in tRNA and develops a platform to screen inhibitors of hDUS2.

6 citations

humanDNA methylation

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BiochemistrybioRxivPreprintNov 3, 2023

Cell type-specific translational regulation by human DUS enzymes

Nathan J. Yu, Wei Hao Dai, Ang Li…·Ralph E. Kleiner

This study identifies DUS enzymes' role in tRNA modification and shows cell type-specific effects on translation.

8 citations

humanbulk RNA-seq

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