Author

Sanshan Jin

Chinese Academy of SciencesORCID 0000-0002-2523-1767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Canrong WuiD· 2 shared H. Eric XuiD· 2 shared Qingning YuaniD· 2 shared Wen HuiD· 2 shared Xinheng HeiD· 2 shared Yi JiangiD· 2 shared Youwei XuiD· 2 shared Antao DaiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiochemistry

Canrong WuORCID

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2 papers

Recent·Most cited

BiochemistryCell DiscoveryPeer-reviewedApr 1, 2025

Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs

Canrong Wu, Chao Zhang, Sanshan Jin…·H. Eric Xu

This study presents cryo-EM structures of hURAT1 bound with anti-gout drugs and uric acid, revealing transport mechanisms and drug inhibition.

28 citationstop 1%

𝕏 PostBluesky

BiophysicsCell DiscoveryPeer-reviewedJun 4, 2024

Structure basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor

Sanshan Jin, Shimeng Guo, Youwei Xu…·Yi Jiang

This study determines the cryo-EM structure of QRFPR bound to 26RFa, revealing the recognition mechanism and aiding drug design for obesity and diabetes.

9 citations

cryo-EMexperimental assay

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