Roxana Ola

The paper identifies a molecular switch in endothelial cells driven by VEGF-A that modulates RNA stability through Phf6 phosphorylation to coordinate angiogenesis.

This study shows that ERK overactivation contributes to endothelial cell hyperproliferation in HHT, suggesting ERK inhibition as a potential therapy.

This study shows Prdm16 enhances Notch signaling in arterial endothelial cells and suppresses venous fate to prevent arteriovenous malformations in zebrafish and human cells.

This study identifies Rnf20's role in regulating cardiac morphogenesis and function through endothelial mechanisms, revealing its impact on extracellular matrix dynamics and angiocrine signaling.