Trude Helen Flo

This study shows that cell-intrinsic complement C3 suppresses IFN-β production in macrophages by limiting IRF3-TBK1 complex formation.

This study identifies NINJ1 as a mediator of plasma membrane rupture in Mtb-infected macrophages, showing it operates independently of canonical cell death pathways and requires the ESX-1 secretion system.

This study uses in vivo microdialysis to longitudinally monitor Aβ and tau in AD mice, showing biomarker dynamics similar to human patients.

This study identifies genetic requirements for growth and virulence in Mycobacterium avium subsp. hominissuis using transposon mutagenesis, revealing shared and unique genes with M. tuberculosis.