Author

Magali Nanchen

University of FribourgORCID 0000-0002-2603-3367Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chantal WickyiD· 2 shared David Rodríguez-CrespoiD· 2 shared Michael StumpeiD· 1 shared Shweta RajopadhyeiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersBiochemistry

Chantal WickyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 7, 2026

The transcription factor LSL-1 interacts with the chromatin factors HIM-17, XND-1 and BRA-2 to promote the germline-specific transcriptional repertoire and to safeguard germ cell fate in C. elegans

Magali Nanchen, David Rodríguez-Crespo, Michael Stumpe, Chantal Wicky

The paper identifies LSL-1's interaction with chromatin factors to maintain germline transcriptional programs and cell fate in C. elegans.

DOI 10.64898/2026.04.05.716469

C. elegansChIP-seq

𝕏 PostBluesky

GeneticsGeneticsPeer-reviewedMar 9, 2022

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in C. elegans

David Rodríguez-Crespo, Magali Nanchen, Shweta Rajopadhye, Chantal Wicky

This study identifies LSL-1 as a key transcriptional activator of germline genes in C. elegans, showing its role in meiotic progression and gene regulation through interaction with heterochromatin proteins.

9 citations

C. elegansChIP-seq

𝕏 PostBluesky