Cell BiologybioRxivPreprint
CCN3-derived peptide BLR-200 impairs YAP activation and attenuates bleomycin-induced skin fibrosis through blocking the generation of Sfrp2-positive fibroblasts
John Nguyen, Alexander Peidl, Pratyusha Chitturi…·Andrew Leask
This paper identifies BLR-200, a CCN3-derived peptide, as an anti-fibrotic agent that impairs YAP activation and reduces bleomycin-induced skin fibrosis by blocking Sfrp2-positive fibroblast generation.
DOI 10.64898/2026.07.07.734740