Author
Harvard UniversityORCID 0000-0002-2703-2438Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Michael C. Mazzola, Ting Zhao, Anna Kiem…·David T. Scadden
The paper shows that IRES/Cap translation increases during hematopoietic and epithelial differentiation under normal conditions, correlating with lower stemness.
Tsuyoshi Fukushima, Trine Ahn Kristiansen, Lai Ping Wong…·David T. Scadden
This study reveals bidirectional fate transitions between myeloid-biased and lineage-balanced hematopoietic stem cells using clonal phylogenetic tracing.
Giulia Schiroli, Vinay Kartha, Fabiana M. Duarte…·David T. Scadden
The paper shows that the epigenetic state of the cell of origin influences susceptibility to Tet2 mutation, with Sox4 promoting dedifferentiation and increased clonal output in hematopoietic stem cells.
Petter Säwén, Mohamed Eldeeb, Eva Erlandsson…·David Bryder
This study shows that adult HSCs contribute to all blood lineages in steady state but decline in contribution with age due to reduced differentiation capacity.