Author

Mrunal Sakharkar

Adimab (United States)ORCID 0000-0002-2717-5201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Jiwon LeeiD· 2 shared Laura M. WalkeriD· 2 shared Margaret E. AckermaniD· 2 shared Nicholas C. CurtisiD· 2 shared Peter F. WrightiD· 2 shared Ruth I. ConnoriD· 2 shared Seungmin Shin· 2 shared Aaron G. SchmidtiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Jiwon LeeORCID

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2 papers

Recent·Most cited

ImmunologyPathogens and ImmunityPeer-reviewedJun 18, 2024

Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2

Ruth I. Connor, Mrunal Sakharkar, Garrett Rappazzo…·Peter F. Wright

This study identifies infection-enhancing antibodies targeting the N-terminal domain of SARS-CoV-2 spike protein, which persist in convalescent patients and may be counteracted by viral mutations.

8 citations

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 8, 2023

Characterization of SARS-CoV-2 Convalescent Patients' Serological Repertoire Reveals High Prevalence of Iso-RBD Antibodies

Nicholas C. Curtis, Seungmin Shin, Andrew P. Hederman…·Jiwon Lee

This study characterizes the serological repertoire of SARS-CoV-2 convalescent patients, revealing a high prevalence of iso-RBD antibodies that do not recognize prefusion-stabilized S, and shows that vaccination with prefusion-stabilized S reduces their prevalence.

DOI 10.1101/2023.09.08.556349

humanproteomics

𝕏 PostBluesky