Tobias Stoeger

The paper evaluates six alveolar macrophage models to identify those best representing in vivo AMs for assessing nanomaterial toxicity, finding AMs GTR and BM-AMs most suitable.

This study shows SARS-CoV-2 E-protein activates CD8+ T cells in mouse lungs via TLR2, observed using intravital microscopy and ex vivo stimulation.

The paper shows that alveolar macrophages recruit neutrophils to sites of nanoparticle deposition in the lung through motility, phagocytosis, and cytokine release.

This study identifies the eATP/P2X7R axis as a driver of nanoparticle-induced neutrophil recruitment in the pulmonary microcirculation using intravital microscopy in mice.

This study uses single-cell RNA-sequencing to analyze how different nanomaterials affect lung inflammation in mice, identifying cell type-specific responses and mechanisms.

This study shows that TiO2 nanotubes and MWCNTs induce different cancer-related changes in vitro, with TiO2 nanotubes disrupting microtubules and inducing binucleated cells, while MWCNTs activate the STING pathway.

The paper predicts nanomaterial-induced chronic inflammation using in vitro measurements and in silico modeling by identifying mechanisms of nanomaterial cycling and quarantining in lung cells.