Alexandre A. S. F. Raposo

The paper identifies gene regulatory modules in thymic regulatory T cells to prioritize variants in complex diseases and uncover mutational hotspots.

The paper identifies cell type-specific alternative splicing changes in lung development, particularly in Vegfa, that may prepare the lung for postnatal function.

This study shows that PADI2-mediated citrullination is essential for oligodendrocyte differentiation, myelination, and motor function, with implications for remyelination therapies.