Author

Rajiv Trehan

National Institutes of HealthORCID 0000-0002-2819-0534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Amran Nur· 2 shared Chi MaiD· 2 shared Firouzeh KorangyiD· 2 shared Francisco Rodríguez-MatosiD· 2 shared Marlaine Soliman· 2 shared Mohamed-Reda BenmebarekiD· 2 shared Patrick HuangiD· 2 shared Shadin GhabraiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Amran Nur

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedMay 7, 2025

✦ In-depth digest

A Paradoxical Tumor Antigen Specific Response in the Liver

Rajiv Trehan, Patrick Huang, Xiao Bin Zhu…·Tim F. Greten

Liver tumors in mice and patients hold many tumor-specific CD8+ T cells that are exhausted; SPP1+ macrophages and a liver-specific intermediate macrophage population are linked to this dysfunction.

81 citationstop 1%

mousehuman

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Cancer BiologybioRxivPreprintJan 23, 2024

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

Kylynda C. Bauer, Rajiv Trehan, Benjamin Ruf…·Tim F. Greten

This study shows that gut microbiota influence liver tumor growth and behavior through the vagus nerve, with cholinergic signaling and CD8+ T cells playing key roles.

18 citations

mouseproteomics

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