Author

Wen Xiong

Baylor College of MedicineORCID 0000-0002-2825-2061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:snRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Hui ZhengiD· 2 shared Marco SardielloiD· 2 shared Ali JazayeriiD· 1 shared Baiping WangiD· 1 shared Bei GaoiD· 1 shared Chuangye Qi· 1 shared Heidi Martini‐StoicaiD· 1 shared Hongjie LiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Hui ZhengORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedApr 1, 2026

TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade

Yan Xiong, Jaiprakash Sharma, Meggie N. Young…·Marco Sardiello

This study identifies an IKK/β-TrCP2 phosphorylation-ubiquitination cascade that regulates TFEB stability, independent of other regulators.

6 citationstop 4%

humanexperimental assay

𝕏 PostBluesky

NeuroscienceNature NeurosciencePeer-reviewedNov 20, 2023

TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy

Baiping Wang, Heidi Martini‐Stoica, Chuangye Qi…·Hui Zheng

This study shows that TFEB-v-ATPase signaling regulates lysosomal function and microglial activation in tauopathy by impairing lysosomal acidification and altering microglia responses.

106 citationstop 1%

𝕏 PostBluesky