Author
Medical University of WarsawORCID 0000-0002-2830-5100Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Tomasz Śpiewla, Karol Czubak, Zofia Pilch…·Joanna Kowalska
The paper develops segmented polyA tail designs to improve DNA stability and mRNA translatability, finding that longer segmented tails significantly enhance protein production.
Marcin Możejko, Daniel Schulz, Krzysztof Gogolewski…·Ewa Szczurek
Cellohood identifies cellular neighborhoods in spatial transcriptomics data, revealing clinically relevant patterns across multiple granularity levels.
Małgorzata Wąsińska-Kałwa, Adam Mamot, Karol Czubak…·Jacek Jemielity
This paper introduces a chemical method to circularize in vitro transcribed RNA, producing chemically circularized RNAs (chem-circRNAs) with high efficiency and compatibility with modifications.
Magdalena Ambrożek-Latecka, Piotr Kozłowski, Grażyna Hoser…·Tomasz Skirecki
This study shows SARS-CoV-2 viroporins ORF3a, E, and M activate inflammasomes in macrophages and induce IL-1α release in pulmonary epithelial and endothelial cells, contributing to immunothrombosis in COVID-19.
Marcin Warmiński, Edyta Trepkowska, Mirosław Śmietański…·Joanna Kowalska
This paper introduces a modified mRNA cap analog, AvantCap, which improves mRNA purification and translational efficiency in vitro and in vivo.