Author

Puran Chen

Karolinska University HospitalORCID 0000-0002-2890-0022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro Gómez-MejíaiD· 1 shared Amanda WeliniD· 1 shared Anna Norrby‐TeglundiD· 1 shared Annelies Sophie ZinkernageliD· 1 shared Danen Mootoosamy CunoosamyiD· 1 shared Ewerton Marques Maggio· 1 shared Johanna SnälliD· 1 shared Kristoffer StråliniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alejandro Gómez-MejíaORCID

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1 paper

Recent·Most cited

MicrobiologymBioPeer-reviewedOct 13, 2025

Alpha-toxin elicited CX3CL1-release via ADAM10 in Staphylococcus aureus pneumoniaimpairs bactericidal function of human monocytes

Srikanth Mairpady Shambat, Puran Chen, Rocky Barilla…·Mattias Svensson

This study shows that S. aureus alpha-toxin induces CX3CL1 release via ADAM10 in lung epithelium, impairing monocyte bactericidal function through CX3CL1-dependent mechanisms.

5 citations

humanproteomics

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