Annelies Sophie Zinkernagel

This study identifies Mnh1 as a key cation/proton antiporter promoting S. aureus phagocytic uptake and intracellular survival in human monocytes, suggesting it as a therapeutic target.

The paper uses single-cell techniques to study agr quorum sensing dynamics in Staphylococcus aureus, revealing differences in AIP sensitivity and community interaction patterns across agr-types.

This study identifies the Fsr quorum sensing system in Enterococcus faecalis as a negative regulator of biofilm growth and inflammation in infective endocarditis.

The paper uses CRISPRi-Seq to identify conserved antibiotic vulnerabilities in S. aureus strains, revealing gene targets for antimicrobial therapies.

This study shows that S. aureus alpha-toxin induces CX3CL1 release via ADAM10 in lung epithelium, impairing monocyte bactericidal function through CX3CL1-dependent mechanisms.

The paper screens Candida albicans isolates for invasiveness by assessing filamentation patterns under simulated host conditions.

This study shows that Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus reduce Streptococcus pyogenes viability in planktonic and biofilm cultures through glycolipid compounds.

ColTapp quantifies bacterial colony growth dynamics from images, enabling analysis of persister cell behavior and improving antibiotic therapy diagnostics.