Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome
Joseph F. Bohlen, Colin M. Cleary, Debamitra Das…·Brady J. Maher
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Johns Hopkins UniversityORCID 0000-0002-2982-3161Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Joseph F. Bohlen, Colin M. Cleary, Debamitra Das…·Brady J. Maher
Isac Lee, Roham Razaghi, Timothy Gilpatrick…·Winston Timp
This study introduces nanoNOMe, a method combining NOMe-seq and nanopore sequencing to profile chromatin accessibility and methylation in human cell lines, revealing phased methylation, large-scale patterns, and structural variations.
Nathan P. Roach, Norah Sadowski, Amelia F. Alessi…·John K. Kim
This study uses direct RNA sequencing to characterize the full-length transcriptome of C. elegans, identifying novel splice and 3UTR isoforms and providing a public dataset.
Rachael E. Workman, Alison D. Tang, Paul S. Tang…·Winston Timp
The paper uses nanopore sequencing to analyze poly(A) RNA from human cells, identifying long transcripts and modifications not captured by traditional methods.