Venkat Gopalan

This study uses native mass spectrometry to reveal the half-site reactivity mechanism of Salmonella FraB, showing how substrate binding and conformational changes regulate catalytic activity in a homodimeric enzyme.

The paper uses solid-state nanopore sensing to analyze conformational changes in a mutated tRNAArgUCU associated with neurodegeneration.

This study identifies TZF1 as a stress granule protein that enhances salt stress tolerance in Arabidopsis by degrading ACA11 mRNA, thereby upregulating salt tolerance genes.