Michael B. Albro

This study validates arthroscopic Raman spectroscopy for quantifying TMJ tissue composition and mechanical properties, showing strong correlations with indentation and tensile modulus.

This paper introduces a method to quantify tissue composition using Raman spectroscopy, validated on cartilage with high accuracy compared to biochemical assays.

This paper develops a sulfonated interpenetrating polymer network to restore degraded cartilage ECM properties and protect against further degradation in osteoarthritis.

The paper introduces an open-source Raman microscopy framework with modular hardware and software for accessible chemical imaging across various applications.

This paper develops LTGF-β conjugated scaffolds to improve neocartilage development by mimicking native TGF-β activation, achieving better mechanical and biochemical properties compared to conventional TGF-β supplementation.

This paper introduces Raman spectral projection tomography (RSPT) for label-free 3-D molecular imaging of tissues with sub-millimeter resolution and demonstrates its application in imaging molecular gradients and extracellular matrix heterogeneities.

The paper investigates the effect of physiologic TGF-beta doses on engineered cartilage composition, finding that lower doses improve neocartilage properties compared to supraphysiologic doses.