Ville O. Paavilainen

This study evaluates the antibacterial, anti-inflammatory, and anticancer activities of solvent-specific extracts from Finnish wild hop tissues.

The paper investigates the lipid scrambling activity of Sec61 and TRAP using molecular dynamics simulations, showing they facilitate lipid flip-flop via a credit card mechanism and are selective for phosphatidylcholine.

This study identifies RRBP1 as a novel peroxisome biogenesis factor in human cells, showing it promotes peroxisome formation and stabilizes peroxisomal proteins.

TSignal is a transformer model that predicts signal peptides and their cleavage sites, showing improved accuracy across various organisms and peptide types.

This study uses phylogenetic analysis and machine learning to predict the pathogenicity of human mtDNA variants, finding many previously uncharacterized variants are likely deleterious.