Author

J Simek

Charles UniversityORCID 0009-0002-7558-3397Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:mechanistic / dynamical model· 1

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Dale TranteriD· 1 shared Denys BiriukoviD· 1 shared Matti JavanaineniD· 1 shared Radek ŠachliD· 1 shared Sarah M. O’KeefeiD· 1 shared Sudeep KarkiiD· 1 shared Ville O. PaavilaineniD· 1 shared

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1 shared paperBiophysics

Dale TranterORCID

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1 paper

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BiophysicsJournal of the American Chemical SocietyPeer-reviewedMay 6, 2025

The Sec61/TRAP Translocon Scrambles Lipids

Matti Javanainen, J Simek, Dale Tranter…·Ville O. Paavilainen

The paper investigates the lipid scrambling activity of Sec61 and TRAP using molecular dynamics simulations, showing they facilitate lipid flip-flop via a credit card mechanism and are selective for phosphatidylcholine.

8 citations

mechanistic / dynamical model

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