Synthetic BiologybioRxivPreprint
A Modular Platform for the Optogenetic Control of Small GTPase Activity in Living Cells Reveals Long-Range RhoA Signaling
Benjamin M. Faulkner, Yuchen He, Daniel Sitrin…·Cliff I. Stains
1 citation
Author
Cliff I. Stains
University of Virginia Cancer CenterORCID 0000-0002-3165-4539Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2025 · peak 2/yrCo-Author Collaboration Network
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- Synthetic BiologyACS Chemical BiologyPeer-reviewed
Split-Small GTPase Reassembly as a Method to Control Cellular Signaling with User-Defined Inputs
Yuchen He, Benjamin M. Faulkner, Rachel S. Weatherford…·Cliff I. Stains
This paper introduces a method to control small GTPase activity using split-GTPases and user-defined chemical inducers, enabling precise temporal regulation of cellular signaling.
4 citations - Cell BiologyAngewandte Chemie International EditionPeer-reviewed
Standardized Parts for Activation of Small GTPase Signaling in Living Cells
Yuchen He, Benjamin M. Faulkner, Meaghan A. Roberti…·Cliff I. Stains.
This paper introduces a split-protein-based method to directly activate small GTPase signaling in living cells using standardized parts that work across the superfamily.