Wen‐Xing Ding

This study shows that autophagy in myofibroblasts drives cyst growth in ADPKD by promoting paracrine stimulation of epithelial cells, with lactate and HIF1 playing key roles.

This study shows that aging worsens alcohol-induced liver damage in mice by increasing inflammation and fat accumulation, and suggests targeting TFEB could help.

This study investigates the distinct roles of VMP1 and TMEM41B in hepatic lipoprotein secretion and autophagy, showing that VMP1 has a more critical role in regulating these processes in MASLD.

This study shows that disrupting mitochondrial fission (DRP1) leads to liver injury and tumorigenesis, while loss of fusion proteins has less impact, and triple knockout mice show reduced tumor development.

This study examines the effects of late-life alcohol exposure on spatial memory and TFEB activity in young and aged mice, finding that aging has a greater impact than alcohol.