S. Lovell

This paper reports the purification, crystallization, and structure of Trichomonas vaginalis pyrophosphate-dependent phosphofructokinase (TvPPi-PFK), revealing its active site and additional ligand-binding sites.

The paper identifies a truncated viral catechol 1,2-dioxygenase from soil phages that retains catalytic activity and expands host metabolic versatility.

This paper describes RUPB-61, an orally available PfPKG inhibitor that prevents liver infection by malaria sporozoites and shows activity against drug-resistant isolates.

This study identifies coumarin derivatives that selectively bind RNA single G bulges, revealing key structural features and using computational and experimental methods to guide rational ligand design.

This study investigates the structure and function of the Fatty Acid Kinase complex in Staphylococcus aureus using modeling, biochemical, and cell-based approaches, revealing key residues and interactions essential for its activity.

This study identifies BB0346 as an essential LolA homolog in Borrelia burgdorferi that functions in a LolB-deficient lipoprotein sorting system, leading to mislocalization of inner membrane lipoproteins.

This study determines the structure of the HSV-1 ICP0 dimer domain, revealing a novel β-barrel fold and its interactions with SUMO1.