Subhrangsu Chatterjee

This study identifies G-quadruplex (G4) structures in the RSV genome and shows they are recognized by ligands and nucleolin, suggesting potential as anti-viral targets.

The paper designs in silico peptides that stabilize VEGF-A G-quadruplexes, reducing gene expression and inhibiting angiogenesis in cancer cells.

The paper identifies a G-quadruplex in the ORAI1 promoter that regulates transcription and Ca2+ dynamics in triple-negative breast cancer.

This study shows that stabilizing G-quadruplex in SMARCAL1 promoter reduces its expression, increases replication stress, and promotes DNA damage in ALT-positive cancer cells, suggesting G4 stabilizers as potential therapeutics.