Author

Yīng Fāng

University of Illinois Urbana-ChampaignORCID 0000-0002-3289-3654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:fungi (other)· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Chengjin YeiD· 2 shared Diego G. DieliD· 2 shared Luis Martínez‐SobridoiD· 2 shared Mohammed NooruzzamaniD· 2 shared Allan C. SpradlingiD· 1 shared Andrew D. Miller· 1 shared Andrew E. FirthiD· 1 shared Chi CheniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

Chengjin YeORCID

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4 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedFeb 27, 2026

The ORF6 accessory protein contributes to SARS-CoV-2 virulence and pathogenicity in the naturally susceptible feline model of infection

Mohammed Nooruzzaman, Salman Latif Butt, Ruchi Rani…·Diego G. Diel

This study shows that deleting ORF6 from SARS-CoV-2 reduces virulence and pathogenicity in cats, with decreased immune suppression and reduced viral replication.

DOI 10.1128/jvi.00644-25

fungi (other)bulk RNA-seq

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Molecular BiologyJournal of VirologyPeer-reviewedApr 7, 2025

An intra-family conserved high-order RNA structure within the M ORF is important for arterivirus subgenomic RNA accumulation and infectious virus production

Pengcheng Shang, Yànhuá Lǐ, Sawsan Napthine…·Yīng Fāng

1 citation

statistical model

𝕏 PostBluesky

MicrobiologyJournal of VirologyPeer-reviewedFeb 29, 2024

The SARS-CoV-2 Spike is a virulence determinant and plays a major role on the attenuated phenotype of Omicron virus in a feline model of infection

Mathias Martins, Mohammed Nooruzzaman, Jessie Lee Cunningham…·Diego G. Diel

This study shows the Omicron BA.1 Spike protein reduces SARS-CoV-2 virulence in a feline model by impairing viral spread and causing less severe disease.

5 citations

fungi (other)experimental assay

𝕏 PostBluesky

GenomicseLifePeer-reviewedNov 1, 2019

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

Oguz Kanca, Jonathan D. Zirin, Jorge García‐Marqués…·Hugo Jozef Bellen

The paper introduces three simplified CRISPR-based methods for DNA insertion in Drosophila, using short homology arms and ssDNA/dsDNA donors to generate transgenic constructs efficiently.

164 citationstop 3%

DrosophilaCRISPR screen

𝕏 PostBluesky