NeurosciencebioRxivPreprint
Adenosine deficiency facilitates CA1 synaptic hyperexcitability in the presymptomatic phase of a knock in mouse model of Alzheimer's disease.
Mattia Bonzanni, Alice Braga, Takashi Saito…·Philip G. Haydon
The paper shows that adenosine deficiency in a mouse model of Alzheimer's disease leads to synaptic hyperexcitability during the asymptomatic phase, which can be restored by pharmacologic or dietary interventions.
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