Developmental BiologybioRxivPreprint
CHD4 and NKX2.2 Cooperate to Regulate Beta Cell Function by Repressing Non-Beta Cell Gene Programs
Dylan Sarbaugh, Thais Gaia Oliveira, Michelle A. Guney…·Lori Sussel
This study identifies CHD4 as a cofactor of NKX2.2 that regulates beta cell function by repressing non-beta cell gene programs, leading to diabetes when disrupted.
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