Author

Saul J. Karpen

Emory UniversityORCID 0000-0002-3379-7592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ahmed M. YounisiD· 1 shared Akshaya BalasubramanianiD· 1 shared Alexander Rodriguez‐PalaciosiD· 1 shared Amber Delmas EliasoniD· 1 shared Arun Jayant SanyaliD· 1 shared Chengyi Jenny Shu· 1 shared Christiane Carter· 1 shared Courtney Lynn HegneriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

Ahmed M. YounisORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintMay 22, 2026

Cholangiocyte RUNX1 Orchestrates Fibrogenic and Inflammatory Signaling to Drive Biliary Fibrosis

Sayed Obaidullah Aseem, J Wang, Ahmed M. Younis…·Huiping Zhou

This study identifies RUNX1 as a key transcriptional regulator of fibrogenic and inflammatory signaling in cholangiocytes, showing its inhibition reduces biliary fibrosis and inflammation in models of cholangiopathy.

DOI 10.64898/2026.05.20.726667

humanmouse

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PhysiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2024

Quantifying forms and functions of intestinal bile acid pools in mice

Koichi Sudo, Amber Delmas Eliason, Shannon M. Soucy…·Mark S. Sundrud

The paper quantifies ileal bile acid pools in mice and shows that Asbt-mediated transport dominates their size and composition, with loss of Asbt reducing pool size and altering transcriptional responses.

14 citations

mousemetabolomics

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