Bo Wang

The paper uses convolutional neural networks to model mutational effects on biochemical phenotypes in SARS-CoV-2 and human ACE2, showing strong predictive power for binding affinity, expression, and antibody escape.

The paper annotates mitochondrial genomes of human, chimpanzee, rhesus macaque, and mouse using 5' and 3' end small RNAs at 1 base-pair resolution, revealing novel functions and conserved sequence blocks.