Philipp Westhoff

This study reports the cryo-EM structure of Pdr5, showing ergosterol binding and its effect on transporter activity, with implications for fungal drug resistance.

This study shows that the root endophyte Pseudomonas argentinensis SA190 enhances drought tolerance in Arabidopsis by supplying glutathione, improving redox balance.

This study shows glycogen deficiency in Synechocystis disrupts day-night energy and redox balance, leading to growth delays and metabolic constraints.

This study shows that endosomal mRNA transport coordinates mitochondrial bioenergetics in fungal hyphae, with Rrm4 essential for mitochondrial protein import and function.

The paper compares trait variation between annual and perennial barley relatives to understand how phylogeny, thermal seasonality, and life history influence their adaptations.

This study measures in vivo enzyme turnover numbers in Vibrio natriegens using multi-omic data fusion, revealing enzymes are 14-fold faster than E. coli and showing machine learning underestimates these kinetics.

This study shows vascular trehalose 6-phosphate (Tre6P) regulates root growth systemically and locally by modulating metabolite allocation between shoots and roots.

The paper identifies a T-DNA-linked inversion-duplication in Arabidopsis that enhances gene expression and exacerbates a light-dependent phenotype in mdh1xme2 mutants.

This study shows that mitochondrial malate metabolism regulates photosynthesis and carbon-nitrogen balance in Arabidopsis under low-light conditions.

This study compares how C3 and C4 Flaveria species respond to phosphate starvation, finding differences in photosynthetic light reaction regulation and stress responses.

This study shows FT1 regulates source-sink interactions, plant longevity, and reproductive development in barley by affecting meristem determinacy and metabolic pathways.

The paper investigates how siderophore exploitation and spatial structure influence microbial community dynamics in iron competition.

This study investigates how acylation of the RTX toxin MbxA enhances membrane disruption by interacting with cholesterol, showing acylation promotes pore formation but not initial membrane binding.

The paper shows that impaired lysine biosynthesis in plants leads to energy stress and reduced survival under darkness by altering metabolic pathways and stress responses.

This study inactivates mitochondrial complex IV in moss to show respiration's role in coordinating carbon and nitrogen metabolism in photosynthetic cells.

This study examines how diverse barley inbreds respond to dry down and moderate drought stress, identifying metabolic and physiological differences associated with drought tolerance.

The paper investigates how Arabidopsis distinguishes between plant growth promoting and pathogenic bacteria, showing CYP71A27 plays a regulatory signaling role rather than a metabolic one in this process.

The paper investigates how host genetics shape microbiome composition across generations, finding that host genotype has a stronger influence than maternal legacy after the first generation.

The paper shows MIC26 regulates metabolic pathways by modulating mitochondrial metabolite exchange, with its role reversing under hyperglycemia.

This study uncouples antiphage and antibacterial properties of aminoglycosides through resistance mechanisms, demonstrating community-wide antiphage defense in bacterial co-cultures.

The paper studies how a geothermal spring community responds to diurnal stressors, revealing structured biotic interactions across domains of life.