Author

Susannah D. Brydges

Regeneron (United States)ORCID 0000-0002-3500-0313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aris N. EconomidesiD· 2 shared Adam E. LockeiD· 1 shared Alan R. ShuldineriD· 1 shared Alexander H. LiiD· 1 shared Anthony MarckettaiD· 1 shared Arunachalam VinayagamiD· 1 shared Bin YeiD· 1 shared Cristopher V. Van HoutiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Aris N. EconomidesORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineeLifePeer-reviewedDec 13, 2024

Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings

Shek Man Chim, Kristen Howell, John Dronzek…·Harikiran Nistala

The paper identifies SLC39A5 as a gene whose loss-of-function variants are associated with reduced type II diabetes risk and improved liver function in metabolic disorders.

3 citations

humanmouse

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Cell BiologybioRxivPreprintJan 29, 2024

Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch

Warren W. Hom, Senem Aykul, Lampros Panagis…·Aris N. Economides

The paper shows that ActA forms non-signaling complexes with ACVR1 that are trafficked to lysosomes and degraded, unlike Activin B, AC, and AB which remain on the surface.

1 citation

humanexperimental assay

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