Margareta J. Hellmann

This study shows that chitin oligomers of specific lengths activate the NLRP3 inflammasome and induce innate immune training through phagocytosis and methyl transferase activity.

This study shows CHI3L1 interacts with chitosan and heparan sulfate to activate TLR2 signaling, revealing HS as a co-receptor for CHI3L1 and its role in inflammation.

This paper shows how domain gain or loss in fungal chitinases determines their function as either antimicrobial or immune-suppressive effectors.

This study uses time-resolved transcriptomics to identify a GH18-CBM5 chitinase in Sebacinales fungi that protects plants against the pathogen Bipolaris sorokiniana.