Deborah Stroka

This study shows that a low-salt diet increases claudin-3 expression in mice, which reduces paracellular sodium permeability, and claudin-3-deficient mice adapt by upregulating other claudins and ENaC to maintain sodium balance.

This study identifies vtRNA1-1 as a short ncRNA that modulates ferroptosis susceptibility in HCC cells by regulating redox homeostasis through a reciprocal loop with NF-κB.

This study investigates how bacteria release ATP during sepsis and shows that bacterial ATP suppresses local immune responses and exacerbates systemic inflammation through outer membrane vesicles.

The paper identifies a germline variant that regulates DPYD gene expression through an enhancer, affecting 5-FU drug resistance.

The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.

This study creates a single-cell time atlas of mouse liver regeneration after partial hepatectomy, revealing Kupffer cells as the first proliferating cell type.

The paper introduces Bayesian correlation as a robust similarity measure for scRNA-seq data, showing it outperforms Pearson correlation in reproducibility and biological relevance.

This study shows that Connexin-43-mediated ATP release from macrophages via TLR-2 and -4 agonists promotes sepsis severity, and inhibiting this pathway improves survival in peritonitis.