Zhen Yan

This study shows that 3q29Del mice exhibit reduced cerebellar volume, motor and vocal impairments, and mitochondrial dysfunction, mirroring human 3q29Del phenotypes.

This study shows that Smarcc2 deficiency causes cognitive and synaptic impairments in mice, which can be rescued by HDAC inhibition.

This study shows that NRMT1 knockout mice develop neurodegeneration and cognitive impairments due to early misregulation of RB and expansion of neural stem cell populations.