Author

Cara L. Brand

University of PennsylvaniaORCID 0000-0002-3559-1790Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael BuszczakiD· 2 shared Anirban DasguptaiD· 1 shared Genevieve T OliveriD· 1 shared Isabella Z. FarkasiD· 1 shared M. H. Levine· 1 shared Mia T LevineiD· 1 shared Nicholas BrowniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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7 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

Michael BuszczakORCID

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintFeb 21, 2026

Adaptive evolution of Topoisomerase II triggers reproductive isolation in Drosophila

Cara L. Brand, Nicholas Brown, Anirban Dasgupta…·M. H. Levine

This study identifies Topoisomerase II divergence as a cause of reproductive isolation between Drosophila species due to its role in resolving DNA satellite-induced topological stress.

1 citation

Drosophilaexperimental assay

𝕏 PostBluesky

Evolutionary BiologyMolecular Biology and EvolutionPeer-reviewedJun 1, 2024

Recurrent duplication and diversification of a vital DNA repair gene family across Drosophila

Cara L. Brand, Genevieve T Oliver, Isabella Z. Farkas…·Mia T Levine

This study investigates the evolutionary diversification of the Spartan gene family in Drosophila, finding recurrent duplication, divergence, and positive selection linked to DNA satellite dynamics.

6 citations

DrosophilaDNA methylation

𝕏 PostBluesky