Mélissa Bowerman

This study shows that mifepristone, a glucocorticoid antagonist, improves SMA disease phenotypes in mice, both alone and when combined with SMN gene therapy.

This study shows that Fn14-depletion improves survival and muscle pathology in SOD1G93A ALS mice, but only when combined with exercise.

The paper establishes international consensus criteria to classify ageing-related pathologies, diseases, and syndromes based on age progression, functional decline, and human evidence.

This study shows Fas activation induces both death and axonal growth in motoneurons, with distinct molecular pathways involved in each response.

This study identifies novel drug treatments for spinal muscular atrophy by integrating multi-omics data and drug perturbation profiles, showing harmine improves disease phenotypes in models.