Pavel I. Kos

The paper identifies rare, long-lived chromatin encounters driven by cohesin-mediated loop extrusion as key to enhancer-promoter communication and shows they explain transcriptional dynamics.

The paper identifies three types of megabase-scale heterochromatin domains in C. elegans using single-molecule tracing and shows their developmental dynamics and structural differences.

The paper investigates cohesin and CTCF chromatin binding dynamics during zebrafish embryogenesis, showing increased binding efficiency and its role in chromatin architecture formation.

The paper uses live-cell imaging to show that chromosomal contacts within TADs are dynamic and stabilized by CTCF and cohesin.