Cynthia Wu

Trex-QTL identifies trans-eQTLs with global effects on molecular phenotypes, showing improved power and replicating known loci in rat brain data.

The paper identifies a quantitative trait locus on chromosome 13 associated with STR expansion propensity in mice, implicating Msh3 in genome-wide mutation patterns.

The paper uses deep neural networks to identify context-specific determinants of transcription factor binding affinity and shows improved prediction performance over existing methods.