Josie E. Parker

This study identifies CYP123 as a key enzyme in mycobacterial lanosterol catabolism, showing it works with CYP51 to oxidize C14-demethylated sterols, expanding the known sterol utilization beyond cholesterol.

This paper describes a clinical case of acquired amphotericin B resistance in Candidozyma auris due to a frameshift mutation in ERG3, showing a fitness cost associated with altered sterol production.

This study identifies Erg3 and Erg6a as key enzymes in the ergosterol biosynthetic pathway of Mucor circinelloides, showing their roles in antifungal drug resistance and virulence.