Jiayin Wang

CellVocal links spatial context to transcriptional dynamics by integrating spatial RNA velocity with cell-cell communication to attribute cell-state transitions to signalling modules and neighbouring cells.

STR-PG provides a scalable framework for short-read STR genotyping by decoupling locus representation from allele content, reducing computational costs while maintaining accuracy.

CellSTIC decodes hierarchical cell-cell communication in spatial multi-omics data by integrating multimodal evidence and organizing interactions into a hierarchical semantic representation.

ZIPcnv improves CNV detection from shallow whole-genome sequencing by addressing zero-inflation and varying CNV sizes, outperforming existing tools.

MRDadaptis improves MRD detection in heterogeneous ctDNA samples by automatically adapting parameters using Bayesian optimization and meta-learning, enhancing detection stability and performance.

RealSeq2 is a preprocessing software for high-throughput sequencing data that includes UMI identification, error correction, and methylation data storage, supporting co-detection of ultra-low frequency mutations and methylation sites.

SOAPTyping is an open-source tool for HLA class I and II allele typing using Sanger sequencing, addressing the lack of free alternatives to commercial software.

The paper introduces a tool for automatically assigning cell types to scRNA-seq clusters using a voting algorithm based on molecular markers, validated on bone marrow data from the Human Cell Atlas.