Author

Kaushik Choudhuri

University of MichiganORCID 0000-0002-3911-027XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:proteomics· 1

Frequent Co-Authors

Fenglei LiiD· 2 shared Benjamin Schmitz· 1 shared Henriette A. RemmeriD· 1 shared Julia BraschiD· 1 shared Wesley I. SundquistiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

Fenglei LiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 30, 2025

T cell ectosomes promote antibody responses through cognate TCR-pMHC interactions

Fenglei Li, Benjamin Schmitz, Henriette A. Remmer…·Kaushik Choudhuri

This study shows that T cell ectosomes, containing TCRs, enhance B cell antibody production by engaging cognate pMHCII, providing a new mechanism of T cell help.

DOI 10.1101/2025.07.30.667776

humanproteomics

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ImmunologybioRxivPreprintOct 1, 2023

Membrane positioning across antigen-induced synaptic contacts tunes CAR-T cell signaling and effector responses

Fenglei Li, Kaushik Choudhuri

This study shows that varying CAR-antigen complex span affects CAR-T cell activation and effector responses, with optimal activation occurring at a span matching TCR-pMHC complexes.

2 citations

humanexperimental assay

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