BiochemistryEMBO Molecular MedicinePeer-reviewed
Inhibition of Asparagine Synthetase Effectively Retards Polycystic Kidney Disease Progression
Sara Clerici, Christine Podrini, Davide Stefanoni…·Alessandra Boletta
This study shows that inhibiting asparagine synthetase (ASNS) with antisense oligonucleotides reduces kidney volume and improves renal function in PKD mice by targeting metabolic pathways.
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