Author

Franklin Garcia

University of California, IrvineORCID 0000-0002-3949-9633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aayushi MahajaniD· 1 shared Alfredo Quiñones‐HinojosaiD· 1 shared Angeliki MelaiD· 1 shared Liang LeiiD· 1 shared Lisa Manier· 1 shared Lisa SprinzeniD· 1 shared Nelson Humala· 1 shared Patrizia CasacciaiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aayushi MahajanORCID

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1 paper

Recent·Most cited

Cancer BiologyCellsPeer-reviewedJan 25, 2024

EZH2 inhibition sensitizes IDH1R132H mutant gliomas to histone deacetylase inhibitor.

Lisa Sprinzen, Franklin Garcia, Angeliki Mela…·Peter Canoll

This study shows that EZH2 inhibition synergizes with HDAC inhibitors to kill IDH1R132H mutant glioma cells by reducing H3K27me3 and increasing H3K27ac.

8 citations

mouseproteomics

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