Jayasri Das Sarma

This study investigates how murine β-coronavirus infection affects oligodendrocyte survival and communication, identifying a novel ERK2 phosphorylation site on Cx47.

This study identifies age-dependent immune mechanisms that confer neuroprotection in young-adult mice infected with β-coronavirus, highlighting differences in immune cell activation and response.

The paper identifies the TGFβ-ANGPT2-Tie2 axis in cancer-associated fibroblasts that reprograms oral cancer cells to an embryonic-like state, linked to poor prognosis.

This study shows that 4-PBA treatment reduces MHV-A59 infectivity and demyelination by preserving Cx43 and ERp29 expression in a murine model of MS.

This study shows that OC43 infection reduces Cx43 expression and impairs gap junction communication in A549 cells, suggesting this pathway could be a therapeutic target for human beta-coronaviruses.

This study shows that Ifit2 deficiency in mice leads to severe viral spread and demyelination in the spinal cord during chronic RSA59 infection.

This study shows that iNOS deficiency in mice worsens virus-induced demyelination by altering inflammatory responses to a beta-coronavirus.